Endocrine Abstracts

Introduction: To evaluate the efficacy of 3 different parathyroid adenoma screening tools (high resolution ultrasonography (USG), technetium Tc 99m-methoxyisobutylisonitrile (MIBI) parathyroid scintigraphy and magnetic resonance imaging (MR)) and to determine factors affecting the detection success rates.Methods: Thirty-nine patients (29 female and 10 male) with primary hyperparathyroidism were included in the study. Patient’s mean age was 53.9&#177...

Background: We investigated the frequency for diagnosis of Hashimoto’s thyroiditis (HT) in obstructive sleep apnea (OSA) patients, based on rising interest in potential links of OSA’s pathogenesis with impaired auto-immune mechanisms.Design and methods: Polysomnography was performed to 245 euthyroid eligible subjects consecutively. Study population divided according to apnea-hypopnea index (AHI) as control (n=59, AHI<5), mild OSA (<i...

Objective: Despite the publication of a recent meta-analysis of elastography in thyroid nodules, further work is necessary on this issue in different populations. In this study we aimed to evaluate the clinical value of elastography in nodular goiter in mild iodine defficient region without excluding according to nodule charecteristics.Materials and methods: This prospective study was conducted between April 2010 and December 2011 in Yildirim Beyazit Dis...

Objective: Insulin resistance may contribute to the development of nodular thyroid disease. Changes in thyroid morphology have been reported in obese patients. In this study, we examined the frequency of nodular thyroid disease in morbid obese patients (BMI>40 kg/m2) and investigated the metabolic parameters which may play a role in thyroid nodule formation.Methods: Three hundred and six morbid obese patients (296 women, 10 men) (age 46.2&...

Objective: Nesfatin-1, was recently discovered in the brain which is derived from nucleobindin2 (NUCB2). Central and peripheral administration of nesfatin-1, inhibits food intake, dose-dependently. Hyperthyroid patients have increased appetite and food intake with a craving for carbohydrate-rich food, at the beginning of disease, but the physiological mechanisms underlying this behavior is not known exactly. In this study, we investigated whether nesfatin-1 is involved in the ...